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ivis spectrum imaging system  (Revvity)


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    Revvity ivis spectrum imaging system
    Ivis Spectrum Imaging System, supplied by Revvity, used in various techniques. Bioz Stars score: 96/100, based on 34889 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/imaging+system+ivis+spectrum/pmc13020017-101-9-13?v=Revvity
    Average 96 stars, based on 34889 article reviews
    ivis spectrum imaging system - by Bioz Stars, 2026-07
    96/100 stars

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    Pharmacokinetics of 25% w/w CBD-loaded Pluronic® F127 polymeric micelles in ASD-like rats. (A) IVIS fluorescence micrographs of rat brains at different time points after i.n. administration of NIR-797-labeled CBD-loaded polymeric micelles, as imaged by IVIS (n = 4). (B) Fluorescence radiance intensity profiles in the brain of rat (n = 4). (C) IVIS fluorescence micrographs of rat olfactory bulbs 90 min after i.n. administration of NIR-797-labeled CBD-loaded polymeric micelles, as imaged by IVIS (n = 4). (D) CBD concentration in rat brains following the i.n. and oral administration of 25% w/w CBD-loaded Pluronic® F127 polymeric micelles and i.n. administration of CBD dissolved in propylene glycol. (E) CBD concentration in rat plasma following the i.n. and oral administration of 25% w/w CBD-loaded Pluronic® F127 polymeric micelles and i.n. administration of CBD dissolved in propylene glycol. In all the PK studies, the i.n. and oral CBD dose was 5 and 15 mg/kg, respectively. All data are presented as mean ± S.E. (n = 4).

    Journal: Bioactive Materials

    Article Title: Nose-to-brain administration of cannabidiol-loaded polymeric micelles improves the core behavioral symptoms of autism spectrum disorder

    doi: 10.1016/j.bioactmat.2026.03.019

    Figure Lengend Snippet: Pharmacokinetics of 25% w/w CBD-loaded Pluronic® F127 polymeric micelles in ASD-like rats. (A) IVIS fluorescence micrographs of rat brains at different time points after i.n. administration of NIR-797-labeled CBD-loaded polymeric micelles, as imaged by IVIS (n = 4). (B) Fluorescence radiance intensity profiles in the brain of rat (n = 4). (C) IVIS fluorescence micrographs of rat olfactory bulbs 90 min after i.n. administration of NIR-797-labeled CBD-loaded polymeric micelles, as imaged by IVIS (n = 4). (D) CBD concentration in rat brains following the i.n. and oral administration of 25% w/w CBD-loaded Pluronic® F127 polymeric micelles and i.n. administration of CBD dissolved in propylene glycol. (E) CBD concentration in rat plasma following the i.n. and oral administration of 25% w/w CBD-loaded Pluronic® F127 polymeric micelles and i.n. administration of CBD dissolved in propylene glycol. In all the PK studies, the i.n. and oral CBD dose was 5 and 15 mg/kg, respectively. All data are presented as mean ± S.E. (n = 4).

    Article Snippet: Imaging was performed using an IVIS® Spectrum CT system from PerkinElmer (Waltham, MA, USA).

    Techniques: Drug discovery, Fluorescence, Labeling, Olfactory, Concentration Assay, Clinical Proteomics